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NECAB3 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | Q96P71 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44,41,22 KDa |
| Antigen Region | 340-368 aa |
| Gene ID | 63941 |
|---|---|
| Other Names | N-terminal EF-hand calcium-binding protein 3, Amyloid beta A4 protein-binding family A member 2-binding protein, Nek2-interacting protein 1, Neuronal calcium-binding protein 3, X11L-binding protein 51, NECAB3, APBA2BP, NIP1, SYTIP2, XB51 |
| Dilution | IF~~1:100 WB~~ 1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | NECAB3 |
|---|---|
| Synonyms | APBA2BP, NIP1, SYTIP2, XB51 |
| Function | Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3. |
| Cellular Location | Golgi apparatus |
| Tissue Location | Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Inhibits the interaction of APBA2 with beta-amyloid precursor protein (APP), and hence allows formation of beta- amyloid.
References
Sugita S.,et al.Neuroscience 112:51-63(2002).
Yoo J.C.,et al.Exp. Cell Res. 292:393-402(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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