PRM3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, FC, E |
---|---|
Primary Accession | Q9NNZ6 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 11269 Da |
Antigen Region | 62-91 aa |
Gene ID | 58531 |
---|---|
Other Names | Protamine-3, Sperm protamine P3, PRM3 |
Target/Specificity | This PRM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the C-terminal region of human PRM3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PRM3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRM3 |
---|---|
Function | Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity). |
Cellular Location | Nucleus. Chromosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PRM3 Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex
References
Imken, L., et al. Mol. Hum. Reprod. 15(11):733-738(2009) Oliva, R. Hum. Reprod. Update 12(4):417-435(2006) Kramer, J.A., et al. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 120(3):467-473(1998)
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