Ataxin 2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q99700 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 140 KDa |
Antigen Region | 721 - 780 aa |
Gene ID | 6311 |
---|---|
Other Names | Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein, ATXN2, ATX2, SCA2, TNRC13 |
Target/Specificity | KLH conjugated synthetic peptide derived from human Ataxin 2 |
Dilution | WB~~ 1:2000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ATXN2 |
---|---|
Synonyms | ATX2, SCA2, TNRC13 |
Function | Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.
References
Pulst S.-M.,et al.Nat. Genet. 14:269-276(1996).
Sanpei K.,et al.Nat. Genet. 14:277-284(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Imbert G.,et al.Nat. Genet. 14:285-291(1996).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.