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Carbonic Anhydrase 5A Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, E |
|---|---|
| Primary Accession | P35218 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35 KDa |
| Gene ID | 763 |
|---|---|
| Other Names | Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA, CA5A, CA5 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CA5A (HGNC:1377) |
|---|---|
| Synonyms | CA5 |
| Function | Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:8356065, PubMed:24530203). Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles (PubMed:24530203). |
| Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Reversible hydration of carbon dioxide. Low activity.
References
Nagao Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7623-7627(1993).
Nagao Y.,et al.Genomics 28:477-484(1995).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Temperini C.,et al.Chemistry 12:7057-7066(2006).
Temperini C.,et al.J. Med. Chem. 49:3019-3027(2006).
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