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p15 INK4b Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC, IHC-P, E |
|---|---|
| Primary Accession | P42772 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 15 KDa |
| Gene ID | 1030 |
|---|---|
| Other Names | Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, MTS-2, p14-INK4b, p15-INK4b, p15INK4B, CDKN2B, MTS2 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CDKN2B |
|---|---|
| Synonyms | MTS2 |
| Function | Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest. |
| Cellular Location | Cytoplasm. Note=Also found in the nucleus |
| Tissue Location | Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
References
Guan K.-L.,et al.Genes Dev. 8:2939-2952(1994).
Hannon G.J.,et al.Nature 371:257-261(1994).
Tsubari M.,et al.Cancer Res. 57:2966-2973(1997).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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