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p18 INK4c Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P42773 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 18 KDa |
| Antigen Region | 101 - 160 aa |
| Gene ID | 1031 |
|---|---|
| Other Names | Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p18 INK4c. The exact sequence is proprietary. |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CDKN2C |
|---|---|
| Synonyms | CDKN6 |
| Function | Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. |
| Tissue Location | Highest levels found in skeletal muscle. Also found in pancreas and heart |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
References
Guan K.-L.,et al.Genes Dev. 8:2939-2952(1994).
Blais A.,et al.Biochem. Biophys. Res. Commun. 247:146-153(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Venkataramani R.,et al.Nat. Struct. Biol. 5:74-81(1998).
Li J.,et al.Biochemistry 38:2930-2940(1999).
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