Collagen 5 alpha 3 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | P25940 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 172 KDa |
| Antigen Region | 231 - 290 aa |
| Gene ID | 50509 |
|---|---|
| Other Names | Collagen alpha-3(V) chain, COL5A3 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Collagen 5 alpha 3. The exact sequence is proprietary. |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | COL5A3 |
|---|---|
| Function | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}. Secreted |
| Tissue Location | Detected in fibroblasts (at protein level) (PubMed:36213313). Detected in urine (at protein level) (PubMed:37453717). |

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Provided below are standard protocols that you may find useful for product applications.
Background
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
References
Imamura Y.,et al.J. Biol. Chem. 275:8749-8759(2000).
Grimwood J.,et al.Nature 428:529-535(2004).
Mann K.,et al.Biol. Chem. Hoppe-Seyler 373:69-75(1992).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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