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Cathepsin E Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, IHC-P, E |
|---|---|
| Primary Accession | P14091 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48 KDa |
| Gene ID | 1510 |
|---|---|
| Other Names | Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CTSE |
|---|---|
| Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
| Cellular Location | Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome |
| Tissue Location | Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
References
Azuma T.,et al.J. Biol. Chem. 264:16748-16753(1989).
Azuma T.,et al.J. Biol. Chem. 267:1609-1614(1992).
Finley E.M.,et al.J. Biol. Chem. 269:31259-31266(1994).
Tatnell P.J.,et al.Biochim. Biophys. Acta 1625:203-206(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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