ETV1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IP, IHC-P, E |
|---|---|
| Primary Accession | P50549 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 55 KDa |
| Gene ID | 2115 |
|---|---|
| Other Names | ETS translocation variant 1, Ets-related protein 81, ETV1, ER81 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ETV1. The exact sequence is proprietary. |
| Dilution | WB~~1:1000 IP~~N/A IHC-P~~N/A E~~N/A |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ETV1 (HGNC:3490) |
|---|---|
| Function | Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
| Tissue Location | Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes. |

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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
References
Jeon I.-S.,et al.Oncogene 10:1229-1234(1995).
Monte D.,et al.Oncogene 11:771-779(1995).
Coutte L.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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