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FSHR Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P23945 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 78, 75, 82 KDa |
| Antigen Region | 261 - 320 aa |
| Gene ID | 2492 |
|---|---|
| Other Names | Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1 |
| Target/Specificity | KLH conjugated synthetic peptide derived from human FSHR |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | FSHR |
|---|---|
| Synonyms | LGR1 |
| Function | G protein-coupled receptor for follitropin, the follicle- stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (PubMed:24058690). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Sertoli cells and ovarian granulosa cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
References
Minegish T.,et al.Biochem. Biophys. Res. Commun. 175:1125-1130(1991).
Tilly J.L.,et al.Endocrinology 131:799-806(1992).
Kelton C.A.,et al.Mol. Cell. Endocrinol. 89:141-151(1992).
Liu X.,et al.Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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