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Glycerol Kinase 2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, ICC, E |
|---|---|
| Primary Accession | Q14410 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 61 KDa |
| Gene ID | 2712 |
|---|---|
| Other Names | Glycerol kinase 2, GK 2, Glycerokinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerol kinase, testis specific 2, GK2, GKP2, GKTA |
| Dilution | WB~~1:1000 IP~~N/A ICC~~N/A E~~N/A |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | GK2 |
|---|---|
| Synonyms | GKP2, GKTA |
| Function | Key enzyme in the regulation of glycerol uptake and metabolism. Essential for male fertility and sperm mitochondrial sheath formation (By similarity). Required for proper arrangement of crescent- like mitochondria to form the mitochondrial sheath during spermatogenesis (By similarity). Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria (PubMed:28852571). |
| Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9WU65}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q9WU65}. Cytoplasm. Note=In sperm the majority of the enzyme is bound to mitochondria {ECO:0000250|UniProtKB:Q9WU65} |
| Tissue Location | Testis-specific (PubMed:33536340). Expressed in the midpiece of spermatozoa (PubMed:28852571) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Key enzyme in the regulation of glycerol uptake and metabolism (By similarity).
References
Sargent C.A.,et al.Hum. Mol. Genet. 3:1317-1324(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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