IPPK Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, ICC, IHC-P, E |
---|---|
Primary Accession | Q9H8X2 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56 KDa |
Gene ID | 64768 |
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Other Names | Inositol-pentakisphosphate 2-kinase, IPK1 homolog, Inositol-1, 6-pentakisphosphate 2-kinase, Ins(1, 6)P5 2-kinase, InsP5 2-kinase, IPPK, C9orf12 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | IPPK |
---|---|
Synonyms | C9orf12 |
Function | Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis. |
Cellular Location | Cytoplasm. Nucleus. |
Tissue Location | Ubiquitously expressed, with high expression in heart, brain, testis and placenta. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
References
Verbsky J.W.,et al.J. Biol. Chem. 277:31857-31862(2002).
Hulme D.J.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Verbsky J.,et al.J. Biol. Chem. 280:29263-29268(2005).
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