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Kallikrein 11 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UBX7 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25 KDa |
| Gene ID | 11012 |
|---|---|
| Other Names | Kallikrein-11, hK11, 3421-, Hippostasin, Serine protease 20, Trypsin-like protease, Kallikrein-11 inactive chain 1, Kallikrein-11 inactive chain 2, KLK11, PRSS20, TLSP |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | KLK11 |
|---|---|
| Synonyms | PRSS20, TLSP |
| Function | Possible multifunctional protease. Efficiently cleaves 'bz- Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. |
| Cellular Location | [Isoform 1]: Secreted. |
| Tissue Location | Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
References
Yoshida S.,et al.Biochim. Biophys. Acta 1399:225-228(1998).
Mitsui S.,et al.Biochem. Biophys. Res. Commun. 272:205-211(2000).
Yousef G.M.,et al.Genomics 63:88-96(2000).
Gan L.,et al.Gene 257:119-130(2000).
Nakamura T.,et al.Prostate 54:299-305(2003).
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