MAST2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, ICC, IHC-P, E |
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Primary Accession | Q6P0Q8 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 205 KDa |
Gene ID | 23139 |
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Other Names | Microtubule-associated serine/threonine-protein kinase 2, MAST2 {ECO:0000312|EMBL:CAH732451} |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MAST2 {ECO:0000312|EMBL:CAH73245.1} |
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Function | Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side Note=Recruited to the sub-membranous area on interaction with CDHR2 |
Tissue Location | Abundant in the testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).
References
Okazaki N.,et al.Carcinogenesis 23:1139-1148(2002).
Gregory S.G.,et al.Nature 441:315-321(2006).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Ohara O.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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