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NFYC Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q13952 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50 KDa |
| Antigen Region | 11 - 70 aa |
| Gene ID | 4802 |
|---|---|
| Other Names | Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NFYC. The exact sequence is proprietary. |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NFYC |
|---|---|
| Function | Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.
References
Nakshatri H.,et al.J. Biol. Chem. 271:28784-28791(1996).
Bellorini M.,et al.Gene 193:119-125(1997).
Dmitrenko V.V.,et al.Gene 197:161-163(1997).
Taira T.,et al.J. Biol. Chem. 274:24270-24279(1999).
Bringuier P.P.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
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