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ELP6 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q0PNE2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29793 Da |
| Antigen Region | 223-252 aa |
| Gene ID | 54859 |
|---|---|
| Other Names | Elongator complex protein 6, Angiotonin-transactivated protein 1, Protein TMEM103, ELP6, ATP1, C3orf75, TMEM103 |
| Target/Specificity | This C3orf75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the C-terminal region of human C3orf75. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ELP6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ELP6 {ECO:0000303|PubMed:22854966, ECO:0000312|HGNC:HGNC:25976} |
|---|---|
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:22854966, PubMed:29332244). Involved in cell migration (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Concentrates in the nucleus upon insulin stimulation. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein has not been specifically defined.
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004)
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$ 150.00
$ 385.00
Cat# AP5163b
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