MRPL12 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | P52815 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21 KDa |
| Antigen Region | 11 - 70 aa |
| Gene ID | 6182 |
|---|---|
| Other Names | 39S ribosomal protein L12, mitochondrial, L12mt, MRP-L12, 5c5-2, MRPL12, RPML12 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MRPL12. The exact sequence is proprietary. |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MRPL12 |
|---|---|
| Synonyms | MRPL7, RPML12 |
| Function | As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation (PubMed:23603806). When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription (PubMed:22003127). Required for POLRMT stability (PubMed:26586915). |
| Cellular Location | Mitochondrion matrix |

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Provided below are standard protocols that you may find useful for product applications.
References
Marty L.,et al.J. Biol. Chem. 271:11468-11476(1996).
Liu J.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Ma F.-R.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Tang T.,et al.J. Biol. Chem. 284:5414-5424(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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