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RECQL4 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O94761 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 133 KDa |
| Gene ID | 9401 |
|---|---|
| Other Names | ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4, RECQL4, RECQ4 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | RECQL4 |
|---|---|
| Synonyms | RECQ4 {ECO:0000303|PubMed:9878247} |
| Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'- overhang in a 3'-5' direction (PubMed:28653661). Does not unwind more than 18 bp of dsDNA (PubMed:28653661). May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA (PubMed:22730300). The core helicase domain binds ssDNA (PubMed:28653661, PubMed:22730300). |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Ubiquitously expressed, with highest levels in thymus and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
DNA-dependent ATPase. May modulate chromosome segregation.
References
Kitao S.,et al.Genomics 54:443-452(1998).
Kitao S.,et al.Genomics 61:268-276(1999).
Kawabe T.,et al.Oncogene 19:4764-4772(2000).
Siitonen H.A.,et al.Hum. Mol. Genet. 12:2837-2844(2003).
Yin J.,et al.Hum. Mol. Genet. 13:2421-2430(2004).
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