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GCFC2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P16383 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 120 KDa |
| Gene ID | 6936 |
|---|---|
| Other Names | GC-rich sequence DNA-binding factor 2, GC-rich sequence DNA-binding factor, Transcription factor 9, TCF-9, GCFC2, C2orf3, GCF, TCF9 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | GCFC2 |
|---|---|
| Synonyms | C2orf3, GCF, TCF9 |
| Function | Involved in pre-mRNA splicing through regulating spliceosome C complex formation (PubMed:24304693). May play a role during late- stage splicing events and turnover of excised introns (PubMed:24304693). |
| Cellular Location | Nucleus, nucleoplasm. Nucleus, nucleolus |
| Tissue Location | Widely expressed in tissues and cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.
References
Kageyama R.,et al.Cell 59:815-825(1989).
Hillier L.W.,et al.Nature 434:724-731(2005).
Olsen J.V.,et al.Cell 127:635-648(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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