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MYO3B Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WXR4 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 152 KDa |
| Gene ID | 140469 |
|---|---|
| Other Names | Myosin-IIIb, MYO3B |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MYO3B. The exact sequence is proprietary. |
| Dilution | WB~~1:1000 E~~N/A |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MYO3B |
|---|---|
| Function | Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q1EG27} |
| Tissue Location | Expressed in retina, kidney and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable actin-based motor with a protein kinase activity.
References
Dose A.C.,et al.Genomics 79:621-624(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Greenman C.,et al.Nature 446:153-158(2007).
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