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ASB15 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WXK1 |
| Other Accession | Q8VHS6, Q8HXA6 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65799 Da |
| Antigen Region | 258-287 aa |
| Gene ID | 142685 |
|---|---|
| Other Names | Ankyrin repeat and SOCS box protein 15, ASB-15, ASB15 |
| Target/Specificity | This ASB15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human ASB15. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ASB15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ASB15 |
|---|---|
| Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ASB15 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
References
Szafranski, K., et al. Genome Biol. 8 (8), R154 (2007)
Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005)
Yoshida, K. Int. J. Mol. Med. 16(2):343-347(2005)
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