P2X1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P51575 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45 KDa |
Gene ID | 5023 |
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Other Names | P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | P2RX1 |
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Synonyms | P2X1 |
Function | Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity). |
Cellular Location | Membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
References
Valera S.,et al.Recept. Channels 3:283-289(1995).
Longhurst P.A.,et al.Biochim. Biophys. Acta 1308:185-188(1996).
Sun B.,et al.J. Biol. Chem. 273:11544-11547(1998).
Dhulipala P.D.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Ennion S.J.,et al.Mol. Pharmacol. 61:303-311(2002).
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