BMS1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q14692 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 146 KDa |
Gene ID | 9790 |
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Other Names | Ribosome biogenesis protein BMS1 homolog, Ribosome assembly protein BMS1 homolog, BMS1, BMS1L, KIAA0187 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | BMS1 (HGNC:23505) |
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Synonyms | BMS1L, KIAA0187 |
Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. |
Cellular Location | Nucleus, nucleolus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity).
References
Nagase T.,et al.DNA Res. 3:17-24(1996).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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