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ECI1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P42126 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33 KDa |
| Antigen Region | 253-302 aa |
| Gene ID | 1632 |
|---|---|
| Other Names | Enoyl-CoA delta isomerase 1, mitochondrial, 5.3.3.8, 3, 2-trans-enoyl-CoA isomerase, Delta(3), Delta(2)-enoyl-CoA isomerase, D3, D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase, ECI1, DCI |
| Dilution | WB~~ 1:1000 |
| Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ECI1 |
|---|---|
| Synonyms | DCI |
| Function | Key enzyme of fatty acid beta-oxidation (Probable). Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2- trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs (PubMed:7818490) (By similarity). The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length (By similarity). |
| Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:P23965} |
| Tissue Location | Expressed in liver (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
References
Janssen U.,et al.Genomics 23:223-228(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kilponen J.M.,et al.Biochem. J. 300:1-5(1994).
Takahashi Y.,et al.Biochem. J. 304:849-852(1994).
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