TMBIM4 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | Q9HC24 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27 KDa |
| Antigen Region | 117-166 aa |
| Gene ID | 51643 |
|---|---|
| Other Names | Protein lifeguard 4, Golgi anti-apoptotic protein, Protein S1R, Transmembrane BAX inhibitor motif-containing protein 4, Z-protein, TMBIM4, GAAP, LFG4 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TMBIM4. The exact sequence is proprietary. |
| Dilution | WB~~ 1:500 |
| Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TMBIM4 |
|---|---|
| Synonyms | GAAP, LFG4 |
| Function | Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release. |
| Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein |

Provided below are standard protocols that you may find useful for product applications.
Background
Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.
References
Goldberger O.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Scherer S.E.,et al.Nature 440:346-351(2006).
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