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Histone H2B (7E2) Mouse mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P33778 |
| Reactivity | Rat |
| Host | Mouse |
| Clonality | Monoclonal Antibody |
| Calculated MW | 13950 Da |
| Gene ID | 3018 |
|---|---|
| Other Names | H2B GL105, H2B.1, Histone H2B type 1B, HIST1H2BB |
| Dilution | WB~~1:100000 IHC-P~~1:500 |
| Name | H2BC3 (HGNC:4751) |
|---|---|
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Cellular Location | Nucleus. Chromosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Swiss-Prot Acc.P33778.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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