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CDT1/DUP Rabbit pAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, FC, IP |
|---|---|
| Primary Accession | Q9H211 |
| Host | Rabbit |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60390 Da |
| Gene ID | 81620 |
|---|---|
| Other Names | DNA replication factor Cdt1, Double parked homolog, DUP, CDT1 {ECO:0000312|EMBL:AAG45181.1} |
| Dilution | WB~~1:1000 IHC~~1:100~500 FC~~1:10~50 IP~~N/A |
| Name | CDT1 {ECO:0000312|EMBL:AAG45181.1} |
|---|---|
| Function | Required for both DNA replication and mitosis (PubMed:11125146, PubMed:14993212, PubMed:21856198, PubMed:22581055, PubMed:26842564). DNA replication licensing factor, required for pre- replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC) (PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene (By similarity). |
| Cellular Location | Nucleus. Chromosome, centromere, kinetochore. Note=Transiently localizes to kinetochores during prometaphase and metaphase |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Swiss-Prot Acc.Q9H211.
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$ 385.00
Cat# AP53528
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