Anti-LDLRAD3 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q86YD5 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37419 Da |
Gene ID | 143458 |
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Other Names | Low-density lipoprotein receptor class A domain-containing protein 3 |
Target/Specificity | Recognizes endogenous levels of LDLRAD3 protein. |
Dilution | WB~~1/500 - 1/1000 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | LDLRAD3 (HGNC:27046) |
---|---|
Synonyms | LRAD3 |
Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation (PubMed:26854353). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to LDLRAD3
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