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Anti-Neuroligin 1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8N2Q7 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 96368 Da |
| Gene ID | 22871 |
|---|---|
| Other Names | KIAA1070; Neuroligin-1 |
| Target/Specificity | Recognizes endogenous levels of Neuroligin 1 protein. |
| Dilution | WB~~1/500 - 1/1000 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NLGN1 |
|---|---|
| Synonyms | KIAA1070 |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep (By similarity). The protein is involved in nervous system development. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q62765} Postsynaptic density {ECO:0000250|UniProtKB:Q62765}. Synaptic cleft {ECO:0000250|UniProtKB:Q62765}. Synaptic cell membrane {ECO:0000250|UniProtKB:Q62765}. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1 {ECO:0000250|UniProtKB:Q62765} |
| Tissue Location | Expressed in the blood vessel walls (at protein level). Highly expressed in brain through prenatal stages, and at lower levels in pancreas islet beta cells. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to Neuroligin 1
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$ 350.00
Cat# AP53827
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