Anti-Serpin B3/4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | P29508 |
| Other Accession | P48594 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44565 Da |
| Gene ID | 6317 |
|---|---|
| Other Names | SERPINB3; SCCA; SCCA1; Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Serpin B3/4. The exact sequence is proprietary. |
| Dilution | WB~~1/500 - 1/1000 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SERPINB3 |
|---|---|
| Synonyms | SCCA, SCCA1 |
| Function | May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
| Cellular Location | Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level |
| Tissue Location | Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). |

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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to Serpin B3/4
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