Anti-ZC3H4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q9UPT8 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 140257 Da |
Gene ID | 23211 |
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Other Names | C19orf7; KIAA1064; Zinc finger CCCH domain-containing protein 4 |
Target/Specificity | Recognizes endogenous levels of ZC3H4 protein. |
Dilution | WB~~1/500 - 1/1000 IH~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ZC3H4 {ECO:0000303|PubMed:33913806, ECO:0000312|HGNC:HGNC:17808} |
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Function | RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) (PubMed:33913806, PubMed:33767452). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein (PubMed:33913806, PubMed:33767452). Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome (PubMed:33913806, PubMed:33767452). The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs (PubMed:33767452). |
Cellular Location | Chromosome. Note=Recruited at sites of high RNA polymerase II occupancy |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to ZC3H4
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