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TRMT11 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q7Z4G4 |
| Other Accession | Q05B63, NP_001026882.2 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53421 Da |
| Antigen Region | 303-332 aa |
| Gene ID | 60487 |
|---|---|
| Other Names | tRNA (guanine(10)-N2)-methyltransferase homolog, 211-, tRNA guanosine-2'-O-methyltransferase TRM11 homolog, TRMT11, C6orf75 |
| Target/Specificity | This TRMT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human TRMT11. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRMT11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRMT11 (HGNC:21080) |
|---|---|
| Function | Catalytic subunit of the TRMT11-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine- dependent N(2)-methylation of guanosine nucleotide at position 10 (m2G10) in tRNAs (PubMed:37283053). This is one of the major tRNA (guanine-N(2))-methyltransferases (PubMed:37283053). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
References
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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