MYPN Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q86TC9 |
Reactivity | Rat, Pig, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 145 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human MYPN |
Epitope Specificity | 901-1000/1320 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Bound to sarcomere both at the Z-line periphery and in the central I-band region. |
SIMILARITY | Belongs to the myotilin/palladin family.Contains 5 Ig-like (immunoglobulin-like) domains. |
SUBUNIT | Interacts with TTN/titin, NEB, NEBL, ACTN2 and CARP. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
Gene ID | 84665 |
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Other Names | Myopalladin, 145 kDa sarcomeric protein, MYPN, MYOP |
Target/Specificity | Expressed in adult skeletal muscle and fetal heart. |
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MYPN |
---|---|
Synonyms | MYOP |
Function | Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines. |
Cellular Location | Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril, sarcomere, Z line. Note=Bound to sarcomere both at the Z-line periphery and in the central I-band region. |
Tissue Location | Expressed in adult skeletal muscle and fetal heart. |

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