UBXD2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q92575 |
Reactivity | Rat, Pig, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56778 Da |
Gene ID | 23190 |
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Other Names | UBX domain-containing protein 4, Erasin, UBX domain-containing protein 2, UBXN4, KIAA0242, UBXD2, UBXDC1 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | UBXN4 |
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Synonyms | KIAA0242, UBXD2, UBXDC1 |
Function | Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD (PubMed:19822669). |
Cellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER |
Tissue Location | Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas Accumulates in Alzheimer disease-afflicted brains (at protein level) |
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