DYX1C1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q8WXU2 |
Reactivity | Rat, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 48527 Da |
Gene ID | 161582 |
---|---|
Other Names | Dynein assembly factor 4, axonemal {ECO:0000312|HGNC:HGNC:21493}, Dyslexia susceptibility 1 candidate gene 1 protein, DNAAF4 (HGNC:21493), DYX1C1, EKN1 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | DNAAF4 (HGNC:21493) |
---|---|
Synonyms | DYX1C1, EKN1 |
Function | Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
Cellular Location | Nucleus. Cytoplasm. Dynein axonemal particle. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q5VJS5} |
Tissue Location | Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells. |
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