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FNDC4 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC |
|---|---|
| Primary Accession | Q9H6D8 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25159 Da |
| Gene ID | 64838 |
|---|---|
| Other Names | Fibronectin type III domain-containing protein 4, Fibronectin type III repeat-containing protein 1, FNDC4, FRCP1 |
| Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | FNDC4 |
|---|---|
| Synonyms | FRCP1 |
| Function | Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to down-regulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by down-regulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. |
| Cellular Location | Membrane; Single-pass type I membrane protein. Secreted {ECO:0000250|UniProtKB:Q3TR08}. Note=The N-terminus is probably cleaved to release a secreted extracellular portion of the protein {ECO:0000250|UniProtKB:Q3TR08} |
| Tissue Location | Up-regulated in colon cells of patients with inflammatory bowel disease (IBD). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP55087
Ordering Information
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