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Vinexin Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | O60504 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 75341 Da |
| Gene ID | 10174 |
|---|---|
| Other Names | Vinexin, SH3-containing adapter molecule 1, SCAM-1, Sorbin and SH3 domain-containing protein 3, SORBS3, SCAM1 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SORBS3 |
|---|---|
| Synonyms | SCAM1 |
| Function | Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain. |
| Cellular Location | [Isoform Alpha]: Cell junction. Cytoplasm, cytoskeleton. Note=Localized at cell- extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesion and cell-cell adhesion sites |
| Tissue Location | Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle and pancreas. Isoform beta is especially found in liver |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP55265
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