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CD99L2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q8TCZ2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human CD99L2 |
| Epitope Specificity | 81-187/262 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cell membrane. Cell junction. |
| SIMILARITY | Belongs to the CD99 family. |
| Post-translational modifications | O-glycosylated. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | May function as a homophilic adhesion molecule. Functions in leukocyte-endothelial cell interactions during leukocyte extravasation, and in particular, at the diapedesis step. Does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis. |
| Gene ID | 83692 |
|---|---|
| Other Names | CD99 antigen-like protein 2, MIC2-like protein 1, CD99, CD99L2, MIC2L1 |
| Target/Specificity | Expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis and uterus. Lower expression seen in thymus. Expressed in E18 uterus and placenta. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | CD99L2 |
|---|---|
| Synonyms | MIC2L1 |
| Function | Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein; Extracellular side. Cell junction. Secreted |
| Tissue Location | Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Expressed in many tissues, with low expression in thymus. |
Research Areas
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Application Protocols
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$ 385.00
Cat# AP55266
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