Constitutive androstane receptor Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q14994 |
Reactivity | Chimpanzee |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39942 Da |
Gene ID | 9970 |
---|---|
Other Names | Nuclear receptor subfamily 1 group I member 3, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, CAR, Orphan nuclear receptor MB67, NR1I3, CAR |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | NR1I3 |
---|---|
Synonyms | CAR |
Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. |
Cellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7. |
Tissue Location | Predominantly expressed in liver. |
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