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DTD1/HARS2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q8TEA8 |
| Reactivity | Rat, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human DTD1 |
| Epitope Specificity | 1-100/209 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DTD family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein is found in the cytoplasm. [provided by RefSeq, Jul 2008] |
| Gene ID | 92675 |
|---|---|
| Other Names | D-aminoacyl-tRNA deacylase 1, Histidyl-tRNA synthase-related, DTD1, C20orf88, DUEB, HARS2 |
| Target/Specificity | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | DTD1 |
|---|---|
| Synonyms | C20orf88, DUEB, HARS2 |
| Function | Possible ATPase (PubMed:15653697) involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes (PubMed:20065034). |
| Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0} Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034) |
| Tissue Location | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP55575
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