TMEM157 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q8TBP5 |
Reactivity | Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 17 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human TMEM157 |
Epitope Specificity | 81-160/190 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Membrane. |
SIMILARITY | Belongs to the FAM174 family. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | TMEM157 is 190 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
Gene ID | 345757 |
---|---|
Other Names | Membrane protein FAM174A, Hepatitis C virus NS5A-transactivated protein 6, HCV NS5A-transactivated protein 6, Transmembrane protein 157, FAM174A, NS5ATP6, TMEM157 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | FAM174A |
---|---|
Synonyms | NS5ATP6, TMEM157 |
Cellular Location | Membrane; Single-pass type I membrane protein |

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