TAMM41 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q96BW9 |
| Reactivity | Rat, Pig, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human C3ORF31 |
| Epitope Specificity | 101-200/316 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Mitochondrion (By similarity). |
| SIMILARITY | Belongs to the MMP37/TAM41 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | C3orf31 (chromosome 3 open reading frame 31), also known as MGC16471 or DKFZp434E0519, is a 316 amino acid mitochondrial protein that belongs to the MMP37 family and may be involved in translocation of transit peptide-containing proteins across the mitochondrial inner membrane. C3orf24 is encoded by a gene that maps to human chromosome 3p25.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Gene ID | 132001 |
|---|---|
| Other Names | Phosphatidate cytidylyltransferase, mitochondrial, 2.7.7.41, CDP-diacylglycerol synthase, CDP-DAG synthase, Mitochondrial translocator assembly and maintenance protein 41 homolog, TAM41, TAMM41, C3orf31 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | TAMM41 |
|---|---|
| Synonyms | C3orf31 |
| Function | Catalyzes the conversion of phosphatidic acid (PA) to CDP- diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:D3ZKT0}; Peripheral membrane protein {ECO:0000250|UniProtKB:D3ZKT0}; Matrix side {ECO:0000250|UniProtKB:P53230} |

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