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mucin3/MUC3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q02505 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 264 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human mucin3 |
| Epitope Specificity | 1501-1600/1719 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Isoform 1: Membrane; Single-pass membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted. |
| SIMILARITY | Contains 1 EGF-like domain. Contains 1 SEA domain. |
| Post-translational modifications | Highly O-glycosylated and probably also N-glycosylated. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | MUC3 (Mucin 3) is an intestinal glycoprotein distributed in the colon and rectum, and to a lesser extent in breast, lung and salivary tissues. It is involved in conferring mucous visoelasticity. |
| Gene ID | 4584 |
|---|---|
| Other Names | Mucin-3A, MUC-3A, Intestinal mucin-3A, MUC3A (HGNC:7513) |
| Target/Specificity | Broad specificity; small intestine, colon,colonic tumors, heart, liver, thymus, prostate, pancreas and gallbladder. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | MUC3A (HGNC:7513) |
|---|---|
| Function | Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. |
| Cellular Location | [Isoform 1]: Membrane; Single-pass membrane protein [Isoform 3]: Secreted [Isoform 5]: Secreted. |
| Tissue Location | Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP55906
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