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GPR162 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GPR162 Polyclonal Antibody AP55974
    Sample:
    Brain (Mouse) Lysate at 40 ug
    Primary: Anti-GPR162 (bs-15386R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 64 kD
    Observed band size: 63 kD
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-F, IF, ICC, E
Primary Accession Q16538
Reactivity Rat, Pig, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 64 KDa
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human GPR162
Epitope Specificity 111-210/588
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION Cell membrane; Multi-pass membrane protein (By similarity).
SIMILARITY Belongs to the G-protein coupled receptor 1 family.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR162 is a 588 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. Existing as two alternatively spliced isoforms, the gene encoding GPR162 maps to human chromosome 12p13.31. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Additional Information
Gene ID 27239
Other Names Probable G-protein coupled receptor 162, Gene-rich cluster gene A protein, GPR162, GRCA
Dilution WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Format0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name GPR162
Synonyms GRCA
Function Orphan receptor.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)
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$ 385.00
Cat# AP55974
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