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> home > Products > Primary Antibodies > Antibody Collections > Inflammatory response > REG3G Antibody (Center)
REG3G Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 8
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q6UW15 |
| Other Accession | NP_001008388.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19330 Da |
| Antigen Region | 89-116 aa |
| Gene ID | 130120 |
|---|---|
| Other Names | Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 165 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B |
| Target/Specificity | This REG3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids of human REG3G. |
| Dilution | WB~~1:2000 FC~~1:10~50 IHC-P~~1:25 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | REG3G Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REG3G (HGNC:29595) |
|---|---|
| Synonyms | PAP1B |
| Function | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854} |
| Tissue Location | Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
REG3G might be a stress protein involved in the control of bacterial proliferation (By similarity).
References
Taylor-Fishwick, D.A., et al. J. Histochem. Cytochem. 56(2):183-191(2008)
Hamblet, N.S., et al. Pancreas 36(1):1-9(2008)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Laurine, E., et al. Biochim. Biophys. Acta 1727(3):177-187(2005)
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$ 150.00
$ 385.00
Cat# AP5606c
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