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FUT10 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q6P4F1 |
| Reactivity | Rat, Chimpanzee, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 56094 Da |
| Gene ID | 84750 |
|---|---|
| Other Names | Alpha-(1, 3)-fucosyltransferase 10, 2.4.1.-, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10, FUT10 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | FUT10 {ECO:0000303|PubMed:19088067, ECO:0000312|HGNC:HGNC:19234} |
|---|---|
| Function | Protein O-fucosyltransferase that specifically catalyzes O- fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1 (PubMed:39775168). Attaches fucose through an O-glycosidic linkage (PubMed:39775168). O- fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion (PubMed:39775168). May also show alpha-(1,3)-fucosyltransferase activity toward the innermost N- acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors (PubMed:19088067). However, this was tested with a library of synthetic substrates and this activity is unsure in vivo (PubMed:19088067). May be involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein [Isoform 4]: Golgi apparatus. Lysosome |
| Tissue Location | Expressed in lung, digestive tract, gall bladder, placenta, kidney, uterus and brain. Not detected in spleen, heart, muscle, liver and pancreas. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP56174
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