FUT10 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
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Primary Accession | Q6P4F1 |
Reactivity | Rat, Chimpanzee, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56094 Da |
Gene ID | 84750 |
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Other Names | Alpha-(1, 3)-fucosyltransferase 10, 2.4.1.-, Fucosyltransferase X, Fuc-TX, FucT-X, Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10, FUT10 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | FUT10 {ECO:0000303|PubMed:19088067, ECO:0000312|HGNC:HGNC:19234} |
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Function | Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation (PubMed:19088067). Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (By similarity). |
Cellular Location | [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein [Isoform 5]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein |
Tissue Location | Expressed in lung, digestive tract, gall bladder, placenta, kidney, uterus and brain. Not detected in spleen, heart, muscle, liver and pancreas. |
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