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GALNTL1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q8N428 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 63 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GALNTL1 |
| Epitope Specificity | 51-150/558 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Golgi apparatus membrane; Single pass type II membrane protein |
| SIMILARITY | Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.Contains 1 ricin B-type lectin domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-TL1 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1), also known as GALNT16, is a 588 amino acid single-pass type II membrane protein belonging to the glycosyltransferase 2 family, which localizes to the Golgi apparatus. GalNAc-TL1 utilizes manganese and calcium as cofactors, and catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, which involves the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Containing one ricin B-type lectin domain, GalNAc-TL1 exists as two alternatively spliced isoforms. |
| Gene ID | 57452 |
|---|---|
| Other Names | Polypeptide N-acetylgalactosaminyltransferase 16, 2.4.1.41, Polypeptide GalNAc transferase 16, GalNAc-T16, Polypeptide GalNAc transferase-like protein 1, GalNAc-T-like protein 1, pp-GaNTase-like protein 1, Polypeptide N-acetylgalactosaminyltransferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1, GALNT16, GALNTL1, KIAA1130 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | GALNT16 |
|---|---|
| Synonyms | GALNTL1, KIAA1130 |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 385.00
Cat# AP56181
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