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FGFBP3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FGFBP3 Antibody (C-term) AP5629b
    All lanes : Anti-FGFBP3 Antibody (C-term) at 1:1000 dilution Lane 1: human brain lysate Lane 2: HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - FGFBP3 Antibody (C-term) AP5629b
    FGFBP3 Antibody (C-term) (Cat. #AP5629b) western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the FGFBP3 antibody detected FGFBP3 protein (arrow).
    detail
  • IHC-P - FGFBP3 Antibody (C-term) AP5629b
    FGFBP3 Antibody (C-term) (Cat. #AP5629b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGFBP3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - FGFBP3 Antibody (C-term) AP5629b
    FGFBP3 Antibody (C-term) (Cat. #AP5629b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q8TAT2
Other Accession NP_689642.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27590 Da
Antigen Region 181-210 aa
Additional Information
Gene ID 143282
Other Names Fibroblast growth factor-binding protein 3, FGF-BP3, FGF-binding protein 3, FGFBP-3, FGFBP3, C10orf13
Target/Specificity This FGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the C-terminal region of human FGFBP3.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGFBP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGFBP3
Synonyms C10orf13
Function Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
Cellular Location Secreted.
Citations ( 0 )

References

Zhang, W., et al. J. Biol. Chem. 283(42):28329-28337(2008)
Deloukas, P., et al. Nature 429(6990):375-381(2004)

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$ 365.00
$ 140.00
Cat# AP5629b
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