KIAA1024 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9UPX6 |
Reactivity | Rat, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 102993 Da |
Gene ID | 23251 |
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Other Names | Major intrinsically disordered Notch2-binding receptor 1, Membrane integral NOTCH2-associated receptor 1, Ubiquitination and mTOR signaling protein, MINAR1 {ECO:0000303|PubMed:29329397} |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MINAR1 {ECO:0000303|PubMed:29329397} |
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Function | Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR (PubMed:30080879). Negatively regulates angiogenesis (PubMed:29329397). Negatively regulates cell growth (PubMed:29329397, PubMed:30080879). Negatively regulates neurite outgrowth in hippocampal neurons (By similarity). |
Cellular Location | Cell membrane; Single-pass type IV membrane protein |
Tissue Location | Widely expressed, including in breast epithelial cells and endothelial cells (at protein level). Expression is down- regulated in advanced breast tumors (at protein level) |
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