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JAKMIP3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q5VZ66 |
| Reactivity | Rat, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 98 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human JAKMIP3 |
| Epitope Specificity | 301-400/844 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Golgi apparatus |
| SIMILARITY | Belongs to the JAKMIP family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | JAKMIP3 is an 844 amino acid protein that belongs to the JAKMIP family. Localizing to the Golgi apparatus, JAKMIP3 is expressed in the central nervous system, as well as endocrine tissue, heart, testis and prostate. Existing as two alternatively spliced isoforms, the gene encoding JAKMIP3 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria |
| Gene ID | 282973 |
|---|---|
| Other Names | Janus kinase and microtubule-interacting protein 3, Neuroendocrine long coiled-coil protein 2, JAKMIP3, C10orf14, C10orf39, JAMIP3, NECC2 |
| Target/Specificity | Specifically expressed in the CNS and endocrine tissues. Also detected in other tissues including heart,testis and prostate. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | JAKMIP3 |
|---|---|
| Synonyms | C10orf14, C10orf39, JAMIP3, NECC2 |
| Cellular Location | Golgi apparatus. |
| Tissue Location | Specifically expressed in the CNS and endocrine tissues. Also detected in other tissues including heart, testis and prostate. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 385.00
Cat# AP56602
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